Research Fellow Department of Cancer and Genomic Sciences 107031 Grade 7

Position Details

Department of Cancer and Genomic Sciences School of Medical Sciences College of Medicine and Health

Location: University of Birmingham Edgbaston Birmingham UK

Full time starting salary is normally in the range 36636 to 46049 with potential progression once in post to 48822

Grade: 7

Full Time Fixed Term contract up to February 2028

Closing date: 1st March 2026

Background

To create and contribute to the creation of knowledge by undertaking a specified range ofactivities within an established research programme and/or specific research project.

Role Summary

A 3 year project investigating PRMT1 and RNA binding proteins in the replication stress response in lung cancer is available within the lab of Prof. Clare Davies.

The post holder is will be expected to undertake novel cutting-edge laboratory-based research within the field of protein arginine methylation and tumour cell biology specified within an MRC funded research programme. They should have experience of working with PRMT enzymes and the replication stress response and ideally RNA binding proteins.

The post holder will:

• Work within specified research grants and projects and contribute to writing bids

• Operate within area of specialism

• Analyse and interpret research findings and results

• Contribute to generating funding

• Contribute to licensing or spin out deals with demonstrated commercial success (such as revenues asset or company sales IP generated) and/or public understanding of the discipline or similar

Main Duties

The responsibilities may include some but not all of the responsibilities outlined below.

• Develop research objectives and proposals for own or joint research with assistance of a mentor if required

• Contribute to writing bids for research funding

• Analyse and interpret data

• Apply knowledge in a way which develops new intellectual understanding

• Disseminate research findings for publication research seminars etc

• Presentresearchresultsthroughpublicationorotherrecognisedformsofoutpute.g. peer-reviewed journals reports and conference presentations at a national/international level

• Contribute to the work of the research team as a whole; through dialogue with colleagues generation of ideas contributing to preparation of grant applications advising on study design problem solving etc

• Contribute to developing new models techniques and methods

• Keepabreastoftheliteratureandmaintainagoodworkingknowledgeofthe background and current developments in the field of the project

• Buildinternal and externalcontactsandparticipateinnetworksfortheexchangeofinformation and for future collaboration

• Supervise students on research related work and provide guidance to PhD students where appropriate to the discipline

• Contribute to enterprise business development and/or public engagement activities of manifest benefit to the College and the University often under supervision of a project leader

• Deal with problems that may affect the achievement of research objectives and deadlines

• Promotes equality and values diversity acting as a role model and fostering an inclusive working culture.

Person Specification

• First degree in area of specialism and a PhD (or in viva awaiting status) relevant to research area or equivalent qualifications

• At least one authorshippublished in a peer-reviewed scientific journal.

• Practicalexperienceof:

  • Mammalian cell culture

  • SinglemoleculeDNAfiberanalysis

  • SIRF and other PLA-based assays (

  • Working with mouse models of cancer (PIL holder)

  • Microscopy-basedlaboratorytechniques(includingimmunofluorescence)

  • Westernblottingandimmunoprecipitation

  • RNA-sequencing and their analysis

  • Extensive lentiviral experience to generate genetically altered cell lines

  • Molecularbiology(includingprimerdesignqPCRDNA/RNAisolation cloningmutagenesisDNAsequencingexpressionplasmidgeneration)

  • Design and implementation of experiments for Mass Spectrometry

• High level analytical capability

• The ability to work and think independently and to significantly contribute to the planning of a programme of scientific research (critically required with demonstrable evidence)

• Effectiveorganisationalskillsandtheabilitytoprioritiseworktomeetdeadlines

• Fluency in relevant models techniques or methods (see above) and ability to contribute to developing new ones

• Ability to assess resource requirements and use resources effectively

• Understanding of and ability to contribute to broader management/administration processes

• Contribute to the planning and organising of the research programme and/or specific research project

• Co-ordinate own work with others to avoid conflict or duplication of effort

• Knowledge of the protected characteristics of the Equality Act 2010 and how to actively ensure in day to day activity in own area that those with protected characteristics are treated equally and fairly.

Further particulars can be foundhere

Informal enquiries to Clare Davies email:

Use of AI in applications:We want to understand your genuine interest in the role and for the written elements of your application to accurately reflect your own communication style. Applications that rely too heavily on AI tools can appear generic and lack the detail we need to assess your skills and experience. Such applications will unlikely be progressed to interview.

We believe there is no such thing as a typical member of University of Birmingham staff and that diversity in its many forms is a strength that underpins the exchange of ideas innovation and debate at the heart of University life. We are committed to proactively addressing the barriers experienced by some groups in our community and are proud to hold Athena SWAN Race Equality Charter and Disability Confident accreditations. We have an Equality Diversity and Inclusion Centre that focuses on continuously improving the University as a fair and inclusive place to work where everyone has the opportunity to succeed. We are also committed to sustainability which is a key part of our strategy. You can find out more about our work to create a fairer university for everyoneon our website.